Bunazosin

Bunazosin is a potent and selective α1-adrenoceptor antagonist. Bunazosin can be used for antihypertensive and ocular hypotensive research[1].

Product Specifications

CAS Number

[80755-51-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/bunazosin.html

Purity

98.52

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NC1=NC(N2CCN(C(CCC)=O)CCC2)=NC3=CC(OC)=C(OC)C=C13

Molecular Formula

C19H27N5O3

Molecular Weight

373.45

Precautions

H302, H315, H319, H335

References & Citations

[1]Hideaki Hara , et al. Bunazosin, a selective alpha1-adrenoceptor antagonist, as an anti-glaucoma drug: effects on ocular circulation and retinal neuronal damage. Cardiovasc Drug Rev. Spring 2005;23 (1) :43-56. |[2]Hideaki Hara , et al. Bunazosin, a selective alpha1-adrenoceptor antagonist, as an anti-glaucoma drug: effects on ocular circulation and retinal neuronal damage. Cardiovasc Drug Rev. Spring 2005;23 (1) :43-56.