Bunazosin
Bunazosin is a potent and selective α1-adrenoceptor antagonist. Bunazosin can be used for antihypertensive and ocular hypotensive research[1].
Product Specifications
CAS Number
80755-51-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bunazosin.html
Purity
98.52
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC1=NC(N2CCN(C(CCC)=O)CCC2)=NC3=CC(OC)=C(OC)C=C13
Molecular Formula
C19H27N5O3
Molecular Weight
373.45
Precautions
H302, H315, H319, H335
References & Citations
[1]Hideaki Hara , et al. Bunazosin, a selective alpha1-adrenoceptor antagonist, as an anti-glaucoma drug: effects on ocular circulation and retinal neuronal damage. Cardiovasc Drug Rev. Spring 2005;23 (1) :43-56. |[2]Hideaki Hara , et al. Bunazosin, a selective alpha1-adrenoceptor antagonist, as an anti-glaucoma drug: effects on ocular circulation and retinal neuronal damage. Cardiovasc Drug Rev. Spring 2005;23 (1) :43-56.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
α adrenergic receptor
Available Sizes
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