Cirtuvivint
Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor. Cirtuvivint can be used for solid tumors research[1].
Product Specifications
CAS Number
[2143917-62-6]
Product Name Alternative
SM08502
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cirtuvivint.html
Purity
98.28
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC(N2CCN(CC2)C)=NC=C1)NC3=NC=C4C=CC(C5=CN(C)N=C5)=CC4=C3
Molecular Formula
C24H25N7O
Molecular Weight
427.50
References & Citations
[1]Betty Y Tam, et al. The CLK inhibitor SM08502 induces anti-tumor activity and reduces Wnt pathway gene expression in gastrointestinal cancer models. Cancer Lett. 2020 Mar 31;473:186-197.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Curated Selection
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