Amelubant
Product Specifications
UNSPSC Description
Amelubant (BIIL 284) is a potent, oral and long acting LTB4 receptor antagonist, negligibly binds to LTB4 receptor, with Kis of 221 nM and 230 nM in vital cells and membranes. Amelubant (BIIL 284) is a proagent of active metabolites BIIL 260 and BIIL 315. Anti-inflammatory activity[1].
Target Antigen
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Amelubant.html
Purity
99.11
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C1=CC=C(OCC2=CC(COC3=CC=C(C(NC(OCC)=O)=N)C=C3)=CC=C2)C=C1)(C4=CC=C(O)C=C4)C
Molecular Weight
538.63
References & Citations
[1]Birke FW, et al. In vitro and in vivo pharmacological characterization of BIIL 284, a novel and potent leukotriene B(4) receptor antagonist. J Pharmacol Exp Ther. 2001 Apr;297(1):458-66.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19304/Amelubant-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19304/Amelubant-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
346735-24-8
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6006359-01 0.1 mg
NUDT4 (Diphosphoinositol Polyphosphate Phosphohydrolase 2, DIPP-2, Diadenosine 5',5'''-P1,P6-hexaphosphate Hydrolase 2, Nucleoside Diphosphate-linked Moiety X Motif 4, Nudix Motif 4, DIPP2, KIAA0487, HDCMB47P)
Ask
View Details MBS6006359-02 5x 0.1 mg
NUDT4 (Diphosphoinositol Polyphosphate Phosphohydrolase 2, DIPP-2, Diadenosine 5',5'''-P1,P6-hexaphosphate Hydrolase 2, Nucleoside Diphosphate-linked Moiety X Motif 4, Nudix Motif 4, DIPP2, KIAA0487, HDCMB47P)
Ask
View Details MBS2037689-01 0.1 mL
APC/CY7-Linked Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10)
Ask
View Details MBS2037689-02 0.2 mL
APC/CY7-Linked Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10)
Ask
View Details MBS2037689-03 0.5 mL
APC/CY7-Linked Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10)
Ask
View Details