What is the catalog number for RHPS4?

The catalog number for RHPS4 is HY-101089.

What sizes are available for RHPS4?

RHPS4 is available in the following size(s): 5 mg, 10 mg, 50 mg, 100 mg.

How many pack sizes does RHPS4 come in?

RHPS4 is available in 4 different pack sizes.

RHPS4 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures RHPS4?

RHPS4 is manufactured by QuantiMol.

What is the estimated delivery time for RHPS4?

Estimated delivery time for RHPS4 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for RHPS4?

The safety data sheet for RHPS4 is available here: http://file.medchemexpress.com/batch_PDF/HY-101089/RHPS4-SDS-MedChemExpress.pdf.

RHPS4

RHPS4 is a potent telomerase inhibitor (IC50 = 0.33 μM) . RHPS4 is a DNA damage inducer[1][2].

Product Specifications

CAS Number

390362-78-4

UNSPSC

12352005

Target

Apoptosis; Telomerase

Type

Reference compound

Related Pathways

Apoptosis; Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rhps4.html

Purity

99.88

Solubility

DMSO : 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=S([O-])(OC)=O.FC1=CC=C2C(C3=[N+](C)C4=C(C=C(C=C4)F)C5=C3C(N2C)=CC(C)=C5)=C1

Molecular Formula

C23H20F2N2O4S

Molecular Weight

458.48

References & Citations

[1]Jennifer C Cookson, et al. Pharmacodynamics of the G-quadruplex-stabilizing telomerase inhibitor 3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in vitro: activity in human tumor cells correlates with telomere length and can be enhanced, or antagonized, with cytotoxic agents. Mol Pharmacol. 2005 Dec;68 (6) :1551-8.|[2]Erica Salvati, et al. Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect. J Clin Invest. 2007 Nov;117 (11) :3236-47.