PRCC rabbit pAb
This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1) (p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle. [provided by RefSeq, Aug 2010],
Product Specifications
Background
This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1) (p11; q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010]
UniProt
Q92733
Swiss Prot
Q92733
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human PRCC AA range: 74-124
Target
PRCC
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleus .
Gene ID (Human)
5546
Available Sizes
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KCNJ6, ID (KCNJ6, GIRK2, KATP2, KCNJ7, G protein-activated inward rectifier potassium channel 2, BIR1, Inward rectifier K(+) channel Kir3.2, KATP-2, Potassium channel, inwardly rectifying subfamily J member 6) (MaxLight 490)
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