Sweroside (Standard)
Sweroside (Standard) is the analytical standard of Sweroside. This product is intended for research and analytical applications. Sweroside is an iridoid glycoside that targets multiple targets, including the Keap1/Nrf2 axis, NLRP3 inflammasome, SIRT1, NF-κB, AMPK/mTOR pathway, and caspase family. Sweroside promotes Nrf2 nuclear translocation by competitively binding to Keap1. Sweroside also inhibits oxidative stress and NLRP3-mediated pyroptosis by activating Nrf2, inhibits NF-κB inflammatory pathway by activating SIRT1, and promotes autophagy and induces caspase-dependent apoptosis via the AMPK/mTOR pathway. Sweroside has antioxidant, anti-inflammatory, anti-apoptotic, and lipid metabolism regulating activities, and can be used in the research of myocardial ischemia-reperfusion injury, leukemia, acute lung injury, non-alcoholic fatty liver disease, and other fields[1][2][3][4].
Product Specifications
CAS Number
14215-86-2
UNSPSC
12352005
Target
AMPK; Apoptosis; Autophagy; Keap1-Nrf2; NF-κB; NOD-like Receptor (NLR) ; PARP; Pyroptosis; Reference Standards; Sirtuin
Type
Reference Standards
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage; Epigenetics; Immunology/Inflammation; NF-κB; Others; PI3K/Akt/mTOR
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/sweroside-standard.html
Smiles
C=C[C@@H]1[C@@](CCOC2=O)([H])C2=CO[C@H]1O[C@]([C@@H]([C@@H](O)[C@@H]3O)O)([H])O[C@@H]3CO
Molecular Formula
C16H22O9
Molecular Weight
358.34
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Isoform
NLRP3; SIRT1
Available Sizes
Frequently Asked Questions
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