Maceneolignan A
Maceneolignan A is a natural product that can be isolated from mace, the aril of Myristica fragrans (Myristicaceae) . Maceneolignan A inhibits the release of β-hexosaminidase in RBL-2H3 cells, with an IC50 of 48.4 μM. Maceneolignan A inhibits the release of TNF-α in antigen stimulated RBL-2H3 cells, with an IC50 of 63.7 μM[1].
Product Specifications
CAS Number
1967042-42-7
UNSPSC
12352005
Target
TNF Receptor
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/maceneolignan-a.html
Solubility
10 mM in DMSO
Smiles
COC1=C2C([C@H]([C@H](C3=CC(OC)=C(C(OC)=C3)O)O2)C)=CC(/C=C/C)=C1
Molecular Formula
C21H24O5
Molecular Weight
356.41
References & Citations
[1]Morikawa T, et al. Degranulation inhibitors from the arils of Myristica fragrans in antigen-stimulated rat basophilic leukemia cells. J Nat Med. 2018 Mar;72 (2) :464-473.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K0258708 1.0 µg DNA
C8orf17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)
Sign In for Pricing
View Details 