PNC-28 (acetate)
PNC-28 acetate is a peptide from the mdm-2-binding domain (residues 17–26) of the p53 protein which contains a membrane crossing-penetratin sequence. PNC-28 acetate can be used for pancreatic cancer research[1][2].
Product Specifications
UNSPSC
12352209
Target
MDM-2/p53
Type
Peptides
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pnc-28-acetate.html
Purity
98.79
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
[ETFSDLWKLLKKWKMRRNQFWVKVQRG(acetate)]
Molecular Formula
C164H255N47O37S.xC2HF3O2
Molecular Weight
3509.13 (free acid)
References & Citations
[1]Kelley A. Sookraj. QS304. Novel p53-Derived Peptide Induces Rapid Human Pancreatic Cancer Cell Death. 2008, 144 (2), 1.|[2]Michl J, et al. PNC-28, a p53-derived peptide that is cytotoxic to cancer cells, blocks pancreatic cancer cell growth in vivo. Int J Cancer. 2006 Oct 1;119 (7) :1577-85.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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