PKA Regulatory Subunit II Substrate

PKA Regulatory Subunit II Substrate (RII phosphopeptide) is a tool peptide derived from the regulatory subunit Type II (RII) of cyclic AMP-dependent protein kinase (PKA) . PKA Regulatory Subunit II Substrate is commonly used to mimic the phosphorylation of protein kinases and as a specific substrate for protein phosphatases to assess the activities of these enzymes[1].

Product Specifications

CAS Number

[103659-06-9]

Product Name Alternative

RII phosphopeptide

UNSPSC

12352209

Target

PKA

Type

Peptides

Related Pathways

Stem Cell/Wnt; TGF-beta/Smad

Applications

Cancer-Kinase/protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/pka-regulatory-subunit-ii-substrate.html

Purity

99.47

Smiles

OC(C[C@H](N)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(N1[C@@H](CCC1)C(N[C@@H]([C@@H](C)CC)C(N2[C@@H](CCC2)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](COP(O)(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](C)C(N[C@H](C(O)=O)CCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C92H151N28O32P

Molecular Weight

2192.33

References & Citations

[1]Wang Lu, et al. "A novel peptide exerts potent immunosuppression by blocking the two-site interaction of NFAT with calcineurin." Journal of Biological Chemistry 295.9 (2020) : 2760-2770.