Anti-Mouse PD-L2/B7-DC Antibody (TY25)
Anti-Mouse PD-L2/B7-DC Antibody (TY25) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse PD-L2/B7-DC. Anti-Mouse PD-L2/B7-DC Antibody (TY25) blocks PD-L2 binding to PD-1 and blocks PD-1 signaling. Anti-Mouse PD-L2/B7-DC Antibody (TY25) can be used for the researches of inflammation and immunology, such as conjunctivitis and transplantation[1][2][3].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352203
Target
Transmembrane Glycoprotein
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-mouse-pd-l2-b7-dc-antibody-ty25.html
Solubility
10 mM in DMSO
Smiles
[Anti-MousePD-L2/B7-DCAntibody(TY25)]
Molecular Weight
(150 kDa)
References & Citations
[1]Morita M, et al. PD-1/B7-H1 interaction contribute to the spontaneous acceptance of mouse liver allograft. Am J Transplant. 2010 Jan;10 (1) :40-6.|[2]Lewkowich IP, et al. PD-L2 modulates asthma severity by directly decreasing dendritic cell IL-12 production. Mucosal Immunol. 2013 Jul;6 (4) :728-39.|[3]Fukushima A, et al. Involvement of programmed death-ligand 2 (PD-L2) in the development of experimental allergic conjunctivitis in mice. Br J Ophthalmol. 2006 Aug;90 (8) :1040-5.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Frequently Asked Questions
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