Cucurbitacin E (Standard)
Cucurbitacin E (Standard) is the analytical standard of Cucurbitacin E. This product is intended for research and analytical applications. Cucurbitacin E is a natural compound which from Cucurbitaceae plants. Cucurbitacin E significantly suppresses the activity of the cyclin B1/CDC2 complex.
Product Specifications
CAS Number
18444-66-1
Product Name Alternative
α-Elaterin (Standard) ; α-Elaterine (Standard)
UNSPSC
12352211
Target
Autophagy; CDK; Reference Standards
Type
Reference Standards
Related Pathways
Autophagy; Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cucurbitacin-e-standard.html
Smiles
O[C@H](C1)[C@@]([C@@](C)(O)C(/C=C/C(OC(C)=O)(C)C)=O)([H])[C@](C2)(C)[C@]1(C)[C@]3([H])CC=C4C(C)(C)C(C(O)=C[C@@]4([H])[C@]3(C)C2=O)=O
Molecular Formula
C32H44O8
Molecular Weight
556.69
References & Citations
[1]Hsu YC, et al. Therapeutic ROS targeting of GADD45γ in the induction of G2/M arrest in primary human colorectal cancer cell lines by cucurbitacin E. Cell Death Dis. 2014 Apr 24;5:e1198.|[2]Murtaza M, et al. Cucurbitacin E reduces obesity and related metabolic dysfunction in mice by targeting JAK-STAT5 signaling pathway. PLoS One. 2017 Jun 9;12 (6) :e0178910.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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