INU-152
INU-152 is a potent and selective B-Raf inhibitor. INU-152 reduces tumor cell proliferation, enhances autophagy, and induces apoptosis by inhibiting B-Raf activity. INU-152 exhibits significant cytotoxicity against cancer cells transformed with v-Ha-ras (Ras-NIH 3T3) . INU-152 can be utilized in cancer research[1].
Product Specifications
CAS Number
1380228-30-7
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis; Autophagy; Raf
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; MAPK/ERK Pathway
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/inu-152.html
Smiles
FC(C=CC(NS(=O)(C1=COC=C1)=O)=C2F)=C2NC3=NC=CC=C3C4=NC=NC5=C4N=CN5
Molecular Formula
C20H13F2N7O3S
Molecular Weight
469.42
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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