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OSBL8 rabbit pAb

This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],

Product Specifications

Background

This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

UniProt

Q9BZF1

Swiss Prot

Q9BZF1

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human OSBL8 AA range: 290-340

Target

OSBL8

Clonality

Polyclonal

Source

Rabbit

Applications

WB

Concentration

1 mg/ml

Dilution

WB 1:500-2000

Buffer

-20°C/1 year

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

[Isoform 1]: Endoplasmic reticulum membrane ; Single-pass membrane protein . Nucleus membrane . The presence of the N-terminus extension contains an overall negative charge that may explain the weak localization to the cortical endoplasmic reticulum (Probable) . .; [Isoform 3]: Endoplasmic reticulum membrane ; Single-pass membrane protein. Localizes to the cortical endoplasmic reticulum at the endoplasmic reticulum-plasma membrane contact sites. .

Gene ID (Human)

114882

Available Sizes

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