Ingenol 3-monobenzoate
Ingenol 3-monobenzoate (Ingenol 3-benzoate) is a disgust inducing agent. Ingenol 3-monobenzoate can bind to and activate PKC (Ki=0.14 nM), inhibit the gene expression of phosphoenolpyruvate carboxykinase, thereby inhibiting gluconeogenesis, and increasing blood cortisol levels, producing food aversion[1].
Product Specifications
CAS Number
[83036-64-0]
Product Name Alternative
Ingenol 3-benzoate
UNSPSC
12352211
Target
PKC
Type
Natural Products
Related Pathways
Epigenetics; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ingenol-3-monobenzoate.html
Purity
97.30
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@@]12[C@]3(C=C([C@@H]2OC(C4=CC=CC=C4)=O)C)C([C@](C=C([C@H]1O)CO)([H])[C@@]5([H])[C@@](C5(C)C)([H])C[C@H]3C)=O
Molecular Formula
C27H32O6
Molecular Weight
452.54
References & Citations
[1]Kronberg, et al. "Potential aversive compounds in leafy spurge for ruminants and rats." Journal of chemical ecology 21 (1995) : 1387-1399.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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