Eleutherol

Eleutherol is a naphthalene isolated from E. americana with antifungal activities[1]. Eleutherol is against yeasts Candida albicans, C. tropicalis, Saccharomyces cerevisiae and Cryptococcus neoformans with MIC values between 7.8 µg/mL and 250 µg/mL[1]. Eleutherol inhibits α-glucosidase function with an IC50>1.00 mM[2].

Product Specifications

CAS Number

[480-00-2]

UNSPSC

12352005

Target

Fungal; Glycosidase

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/eleutherol.html

Purity

99.99

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1O[C@H](C)C2=C(O)C3=C(OC)C=CC=C3C=C12

Molecular Formula

C14H12O4

Molecular Weight

244.24

References & Citations

[1]Adriana Campos, et al. Antifungal Activity of Pyranonaphthoquinones Obtained from Cipura paludosa Bulbs. Nat Prod Commun. 2015 Sep;10 (9) :1589-92.|[2]Tomohiro Ieyama, et al.α-Glucosidase inhibitors from the bulb of Eleutherine americana. Food Chem.2011 Sep 15;128 (2) :308-11.