Dihydro-β-erythroidine
Dihydro-β-erythroidine is a a competitive nicotinic receptor antagonist. Dihydro-β-erythroidine blocks the discriminative stimulus properties of nicotine. Dihydro-β-erythroidine inhibits the anxiolytic effect of nicotine induced[1][2].
Product Specifications
CAS Number
23255-54-1
UNSPSC
12352005
Target
NAChR
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dihydro-β-erythroidine.html
Solubility
10 mM in DMSO
Smiles
CO[C@H]1CC=C2CCN3CCC4=C([C@@]32C1)CC(OC4)=O
Molecular Formula
C16H21NO3
Molecular Weight
275.34
References & Citations
[1]Shoaib M, et al. Antagonism of stimulus properties of nicotine by dihydro-beta-erythroidine (DHbetaE) in rats. Psychopharmacology (Berl) . 2000 Apr;149 (2) :140-6.|[2]Cheeta S, et al. Antagonism of the anxiolytic effect of nicotine in the dorsal raphe nucleus by dihydro-beta-erythroidine. Pharmacol Biochem Behav. 2001 Dec;70 (4) :491-6.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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