Leucomycin
Leucomycin (Kitasamycin) is an orally active macrolide antibiotic produced by Streptomyces kitasatoensis. Leucomycin has broad-spectrum antibacterial activities against gram-positive and gram-negative bacteria, mycoplasma, leptospira, spirochaetes, rickettsiae and some larger viruses[1][2][3][4][5][6][7].
Product Specifications
CAS Number
1392-21-8
Product Name Alternative
Kitasamycin
UNSPSC
12352005
Hazard Statement
H302
Target
Antibiotic; Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/leucomycin.html
Solubility
DMSO : 110 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
[Leucomycin]
Precautions
H302
References & Citations
[1]PACHTMAN EA, et al. Leucomycin; a new antibiotic. Am J Pharm Sci Support Public Health. 1958 Oct;130 (10) :342-4.|[2]Vézina C, et al. Biosynthesis of kitasamycin (leucomycin) by leucine analog-resistant mutants of Streptomyces kitasatoensis. Antimicrob Agents Chemother. 1979 May;15 (5) :738-46.|[3]La T, et al. Testing the efficacy of kitasamycin for use in the control and treatment of swine dysentery in experimentally infected pigs. Aust Vet J. 2019 Sep 17.|[4]Hassan AB, et al. Pharmacokinetics and tissue residues of kitasamycin in healthy and diseased broilers. Dtsch Tierarztl Wochenschr. 1990 Aug;97 (8) :315-7.|[5]Iwata K, et al. Studies on the in vitro Antibacterial Activity of Leucomycin[J]. The Journal of Antibiotics, Series A, 1962, 15 (6) : 258-265.|[6]Kondo M, et al. Maridomycin, a new macrolide antibiotic. 3. In vitro and in vivo antibacterial activity. J Antibiot (Tokyo) . 1973 Apr;26 (4) :206-14. |[7]Liu G, et al. Quantitative analysis of impurities in leucomycin bulk drugs and tablets: A high performance liquid chromatography-charged aerosol detection method and its conversion to ultraviolet detection method. J Pharm Biomed Anal. 2021 Aug 5;202:114148.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Macrolide
Available Sizes
Frequently Asked Questions
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