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IDO-IN-3

IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 290 nM.

Product Specifications

CAS Number

2070018-30-1

UNSPSC

12352005

Target

Indoleamine 2,3-Dioxygenase (IDO)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/IDO-IN-3.html

Purity

98.97

Solubility

DMSO : 27.5 mg/mL (ultrasonic; warming)

Smiles

O/N=C(NC1=CC(Br)=C(F)C=C1)\C2=NON=C2NCCN

Molecular Formula

C11H12BrFN6O2

Molecular Weight

359.15

References & Citations

[1]Yue EW, et al. INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology. ACS Med Chem Lett. 2017 Mar 6;8 (5) :486-491.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

IDO

Available Sizes

Frequently Asked Questions

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