IDO-IN-3
IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 290 nM.
Product Specifications
CAS Number
[2070018-30-1]
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/IDO-IN-3.html
Purity
98.97
Solubility
DMSO : 27.5 mg/mL (ultrasonic; warming)
Smiles
O/N=C(NC1=CC(Br)=C(F)C=C1)\C2=NON=C2NCCN
Molecular Formula
C11H12BrFN6O2
Molecular Weight
359.15
References & Citations
[1]Yue EW, et al. INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology. ACS Med Chem Lett. 2017 Mar 6;8 (5) :486-491.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IDO
Available Sizes
Curated Selection
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