Glyoxalase I inhibitor 6
Glyoxalase I inhibitor 6 (Compound 9j) is a glyoxalase I (Glo-I) inhibitor with an IC50 of 1.13 μM. Glyoxalase I inhibitor 6 can be used as anticancer agent with low toxicity[1].
Product Specifications
CAS Number
[2455508-19-5]
UNSPSC
12352005
Target
Glyoxalase (GLO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/glyoxalase-i-inhibitor-6.html
Purity
99.26
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)C1=CC(/N=N/C2=CC=C(C)C(S(=O)(N)=O)=C2)=C3C=CC=CC3=C1O
Molecular Formula
C18H15N3O5S
Molecular Weight
385.39
References & Citations
[1]Al-Oudat BA, et al. Design, synthesis and biological evaluation of novel glyoxalase I inhibitors possessing diazenylbenzenesulfonamide moiety as potential anticancer agents. Bioorg Med Chem. 2020 Aug 15;28 (16) :115608.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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