13 (S) -HPODE

13 (S) -HPODE is a linoleic acid metabolite found in several plants and mammals.

Product Specifications

CAS Number

[33964-75-9]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

EGFR; Endogenous Metabolite

Type

Natural Products

Related Pathways

JAK/STAT Signaling; Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/13_S_-HPODE.html

Concentration

320.06 μM * 500 μL in Ethanol

Purity

95.0

Solubility

10 mM in DMSO

Smiles

CCCCC[C@H](OO)/C=C/C=C\CCCCCCCC(O)=O

Molecular Formula

C18H32O4

Molecular Weight

312.44

Precautions

H302, H315, H319, H335

References & Citations

[1]Gardner HW, et al. Soybean lipoxygenase-1 enzymically forms both (9S) - and (13S) -hydroperoxides from linoleic acid by a pH-dependent mechanism. Biochim Biophys Acta. 1989 Feb 20;1001 (3) :274-81.|[2]Reinaud O, et al. Oxidative metabolism of linoleic acid by human leukocytes. Biochem Biophys Res Commun. 1989 Jun 15;161 (2) :883-91.|[3]Glasgow WC, et al. The linoleic acid metabolite, (13S) -hydroperoxyoctadecadienoic acid, augments the epidermal growth factor receptor signaling pathway by attenuation of receptor dephosphorylation. Differential response in Syrian hamster embryo tumor suppressor phenotypes. J Biol Chem. 1997 Aug 1;272 (31) :19269-76.