13 (S) -HPODE
13 (S) -HPODE is a linoleic acid metabolite found in several plants and mammals.
Product Specifications
CAS Number
[33964-75-9]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
EGFR; Endogenous Metabolite
Type
Natural Products
Related Pathways
JAK/STAT Signaling; Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/13_S_-HPODE.html
Concentration
320.06 μM * 500 μL in Ethanol
Purity
95.0
Solubility
10 mM in DMSO
Smiles
CCCCC[C@H](OO)/C=C/C=C\CCCCCCCC(O)=O
Molecular Formula
C18H32O4
Molecular Weight
312.44
Precautions
H302, H315, H319, H335
References & Citations
[1]Gardner HW, et al. Soybean lipoxygenase-1 enzymically forms both (9S) - and (13S) -hydroperoxides from linoleic acid by a pH-dependent mechanism. Biochim Biophys Acta. 1989 Feb 20;1001 (3) :274-81.|[2]Reinaud O, et al. Oxidative metabolism of linoleic acid by human leukocytes. Biochem Biophys Res Commun. 1989 Jun 15;161 (2) :883-91.|[3]Glasgow WC, et al. The linoleic acid metabolite, (13S) -hydroperoxyoctadecadienoic acid, augments the epidermal growth factor receptor signaling pathway by attenuation of receptor dephosphorylation. Differential response in Syrian hamster embryo tumor suppressor phenotypes. J Biol Chem. 1997 Aug 1;272 (31) :19269-76.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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