NF-L Rabbit Polyclonal Antibody

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

68 kDa neurofilament protein antibody 68kDa Neurofilament antibody 68kDa neurofilament protein antibody CMT1F antibody CMT2E antibody FLJ53642 antibody Light molecular weight neurofilament protein antibody NEFL antibody Neurofilament light antibody Neurofilament light polypeptide 68kDa antibody Neurofilament light polypeptide antibody Neurofilament protein, light chain antibody Neurofilament subunit NF L antibody Neurofilament triplet L protein antibody NF-L antibody NF68 antibody NFL antibody NFL_HUMAN antibody

Abbreviation

NEFL; NF68; NFL; Neurofilament light polypeptide; NF-L; 68 kDa neurofilament protein; Neurofilament triplet L protein

Swiss Prot

P07196 Human, P08551 Mouse, P19527 Rat

Cellular Locus

Cell projection, axon, Cytoplasm, cytoskeleton.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within human NF-L aa 1-543 / 543.

Isotype

IgG

Conjugation

Non-conjugated

Type

Rabbit polyclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

Rat brain tissue lysate, mouse hippocampus tissue lysate, rat hippocampus tissue lysate, human brain tissue lysate, SH-SY5Y, human cerebellum tissue, mouse cerebellum tissue, rat cerebellum tissue.