[Tyr8]-Atrial Natriuretic Peptide (5-27), rat

[Tyr8]-Atrial Natriuretic Peptide (5-27), rat is an atrial natriuretic peptide (ANP) analog that relaxes smooth muscle without affecting cGMP levels[1][2].

Product Specifications

CAS Number

[108703-67-9]

UNSPSC

12352209

Target

Natriuretic Peptide Receptor (NPR)

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/tyr8-atrial-natriuretic-peptide-5-27-rat.html

Solubility

10 mM in DMSO

Smiles

OC(C=C1)=CC=C1C[C@H](NC([C@H](CS)NC([C@H](CO)NC([C@@H](N)CO)=O)=O)=O)C(NCC(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(NCC(N[C@@H](CC(C)C)C(NCC(N[C@@H](CS)C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@H](C(N[C@H](C(O)=O)CCCNC(N)=N)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C98H158N34O33S2

Molecular Weight

2404.64

References & Citations

[1]Budzik GP, et, al. Divergence of ANF analogs in smooth muscle cell cGMP response and aorta vasorelaxation: evidence for receptor subtypes. Biochem Biophys Res Commun. 1987 Apr 14;144 (1) :422-31.|[2]Törnell J, et, al. Atrial natriuretic peptide inhibits spontaneous rat oocyte maturation. Endocrinology. 1990 Mar;126 (3) :1504-8.