Co 101244 (hydrochloride)
Co 101244 (PD 174494) hydrochloride is a NR2B-containing NMDA receptor antagonist[1].
Product Specifications
CAS Number
[193356-17-1]
Product Name Alternative
PD 174494 (hydrochloride)
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/co-101244-hydrochloride.html
Purity
99.80
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1(CCN(CCOC2=CC=C(O)C=C2)CC1)CC3=CC=C(C)C=C3.[H]Cl
Molecular Formula
C21H28ClNO3
Molecular Weight
377.90
References & Citations
[1]Ruslan I Stanika, et al. Coupling diverse routes of calcium entry to mitochondrial dysfunction and glutamate excitotoxicity. Proc Natl Acad Sci U S A. 2009 Jun 16;106 (24) :9854-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor
Available Sizes
Curated Selection
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