Co 101244 (hydrochloride)

Co 101244 (PD 174494) hydrochloride is a NR2B-containing NMDA receptor antagonist[1].

Product Specifications

CAS Number

[193356-17-1]

Product Name Alternative

PD 174494 (hydrochloride)

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/co-101244-hydrochloride.html

Purity

99.80

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1(CCN(CCOC2=CC=C(O)C=C2)CC1)CC3=CC=C(C)C=C3.[H]Cl

Molecular Formula

C21H28ClNO3

Molecular Weight

377.90

References & Citations

[1]Ruslan I Stanika, et al. Coupling diverse routes of calcium entry to mitochondrial dysfunction and glutamate excitotoxicity. Proc Natl Acad Sci U S A. 2009 Jun 16;106 (24) :9854-9.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

NMDA Receptor

Available Sizes

Curated Selection

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