Flumequine (Standard)

Flumequine (Standard) is the analytical standard of Flumequine. This product is intended for research and analytical applications. Flumequine (R-802) is a quinolone antibiotic, and acts as a topoisomerase II inhibitor, with an IC50 of 15 μM (3.92 μg/mL) .

Product Specifications

CAS Number

[42835-25-6]

Product Name Alternative

R-802 (Standard)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial; Reference Standards; Topoisomerase

Type

Reference Standards

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Others

Field of Research

Infection; Cancer

Assay Protocol

https://www.medchemexpress.com/flumequine-standard.html

Purity

99.54

Smiles

O=C(C1=CN2C(C)CCC3=C2C(C1=O)=CC(F)=C3)O

Molecular Formula

C14H12FNO3

Molecular Weight

261.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Kashida Y, et al. Mechanistic study on flumequine hepatocarcinogenicity focusing on DNA damage in mice. Toxicol Sci. 2002 Oct;69 (2) :317-21.|[2]Aller-Morán LM, et al. Evaluation of the in vitro activity of flumequine against field isolates of Brachyspira hyodysenteriae. Res Vet Sci. 2015 Dec;103:51-3.|[3]Giraud E, et al. Mechanisms of quinolone resistance and clonal relationship among Aeromonas salmonicida strains isolated from reared fish with furunculosis. J Med Microbiol. 2004 Sep;53 (Pt 9) :895-901.