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URB532

URB532 is an inhibitor for fatty acid amide hydrolase (FAAH) with an IC50 of 396 nM. URB532 increases levels of arachidonic acid acetamide (AEA), palmitoylethanolamide (PEA), and oleamide (OEA) in the rat brain, and exhibits anxiolytic and analgesic effects[1].

Product Specifications

CAS Number

[195140-79-5]

UNSPSC

12352005

Target

FAAH

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/urb532.html

Smiles

O=C(OC1=CC=C(OCC2=CC=CC=C2)C=C1)NCCCC

Molecular Formula

C18H21NO3

Molecular Weight

299.36

References & Citations

[1]Vandevoorde S. Overview of the chemical families of fatty acid amide hydrolase and monoacylglycerol lipase inhibitors. Curr Top Med Chem. 2008;8 (3) :247-67.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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