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L 687781

Product Specifications

CAS Number

[130304-58-4]

UNSPSC Description

L 687781, a papulacandin analog, is a 1,3-beta-D-glucan synthesis inhibitor with antifungal activity (IC50 of 0.16 μg/mL)[1].

Target Antigen

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/l-687781.html

Smiles

OC1C2(OC(CO)C(OC3OC(C(O)C(O)C3O)COC(/C=C/C=C/CCC(O)CC)=O)C1OC(/C=C/C=C/CC(O)/C(C)=C/C=C/CCC(C)CC)=O)C4=C(C=C(O)C=C4O)CO2

Molecular Weight

903.02

References & Citations

[1]K Bartizal, et al. In vitro antifungal activities and in vivo efficacies of 1,3-beta-D-glucan synthesis inhibitors L-671,329, L-646,991, tetrahydroechinocandin B, and L-687,781, a papulacandin. Antimicrob Agents Chemother. 1992 Aug;36(8):1648-57.

Shipping Conditions

Room temperature

Clinical Information

No Development Reported

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