L 687781
Product Specifications
CAS Number
[130304-58-4]
UNSPSC Description
L 687781, a papulacandin analog, is a 1,3-beta-D-glucan synthesis inhibitor with antifungal activity (IC50 of 0.16 μg/mL)[1].
Target Antigen
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/l-687781.html
Smiles
OC1C2(OC(CO)C(OC3OC(C(O)C(O)C3O)COC(/C=C/C=C/CCC(O)CC)=O)C1OC(/C=C/C=C/CC(O)/C(C)=C/C=C/CCC(C)CC)=O)C4=C(C=C(O)C=C4O)CO2
Molecular Weight
903.02
References & Citations
[1]K Bartizal, et al. In vitro antifungal activities and in vivo efficacies of 1,3-beta-D-glucan synthesis inhibitors L-671,329, L-646,991, tetrahydroechinocandin B, and L-687,781, a papulacandin. Antimicrob Agents Chemother. 1992 Aug;36(8):1648-57.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
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