Mapracorat
Mapracorat is a novel non-steroidal selective glucocorticoid receptor agonist.
Product Specifications
CAS Number
887375-26-0
Product Name Alternative
ZK-245186; BOL-303242X
UNSPSC
12352005
Hazard Statement
H361, H373
Target
Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/Mapracorat.html
Purity
99.40
Solubility
DMSO : ≥ 33.6 mg/mL
Smiles
CC(C)(C1=C(OCC2)C2=CC(F)=C1)C[C@@](O)(CNC3=C4C=CC(C)=NC4=CC=C3)C(F)(F)F
Molecular Formula
C25H26F4N2O2
Molecular Weight
462.48
Precautions
H361, H373
References & Citations
[1]Bäumer W , et al. The selective glucocorticoid receptor agonist mapracorat displays a favourable safety-efficacy ratio for the topical treatment of inflammatory skin diseases in dogs. Vet Dermatol. 2017 Feb; 28 (1) :46-e11.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
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