Gemopatrilat
Gemopatrilat (BMS-189921) is an orally active vasopeptidase inhibitor with IC50 value of 12 nM. Gemopatrilat can be used in studies of hypertension and congestive heart failure[1].
Product Specifications
CAS Number
160135-92-2
Product Name Alternative
BMS-189921
UNSPSC
12352005
Target
Angiotensin-converting Enzyme (ACE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/gemopatrilat.html
Smiles
O=C(O)CN1C(C)(C)CCC[C@H](NC([C@@H](S)CC2=CC=CC=C2)=O)C1=O
Molecular Formula
C19H26N2O4S
Molecular Weight
378.49
References & Citations
[1]Robl JA, et al. Vasopeptidase inhibitors: incorporation of geminal and spirocyclic substituted azepinones in mercaptoacyl dipeptides. J Med Chem. 1999 Jan 28;42 (2) :305-11.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
ACE
Frequently Asked Questions
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