Gemopatrilat
Product Specifications
UNSPSC Description
Gemopatrilat (BMS-189921) is an orally active vasopeptidase inhibitor with IC50 value of 12 nM. Gemopatrilat can be used in studies of hypertension and congestive heart failure[1].
Target Antigen
Angiotensin-converting Enzyme (ACE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/gemopatrilat.html
Smiles
O=C(O)CN1C(C)(C)CCC[C@H](NC([C@@H](S)CC2=CC=CC=C2)=O)C1=O
Molecular Weight
378.49
References & Citations
[1]Robl JA, et al. Vasopeptidase inhibitors: incorporation of geminal and spirocyclic substituted azepinones in mercaptoacyl dipeptides. J Med Chem. 1999 Jan 28;42(2):305-11.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-123381/Gemopatrilat-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-123381/
Clinical Information
Phase 2
CAS Number
160135-92-2
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