Gemopatrilat

Gemopatrilat (BMS-189921) is an orally active vasopeptidase inhibitor with IC50 value of 12 nM. Gemopatrilat can be used in studies of hypertension and congestive heart failure[1].

Product Specifications

CAS Number

[160135-92-2]

Product Name Alternative

BMS-189921

UNSPSC

12352005

Target

Angiotensin-converting Enzyme (ACE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/gemopatrilat.html

Smiles

O=C(O)CN1C(C)(C)CCC[C@H](NC([C@@H](S)CC2=CC=CC=C2)=O)C1=O

Molecular Formula

C19H26N2O4S

Molecular Weight

378.49

References & Citations

[1]Robl JA, et al. Vasopeptidase inhibitors: incorporation of geminal and spirocyclic substituted azepinones in mercaptoacyl dipeptides. J Med Chem. 1999 Jan 28;42 (2) :305-11.