Losartan-d4
Losartan-d4 is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.
Product Specifications
CAS Number
[1030937-27-9]
Product Name Alternative
DuP-753 D4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Angiotensin Receptor
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Cardiovascular Disease
Purity
99.93
Solubility
10 mM in DMSO|DMSO : ≥ 42.69mg/mL|Ethanol : ≥ 42.69mg/mL
Smiles
OCC1=C(Cl)N=C(CCCC)N1CC2=C([2H])C([2H])=C(C3=CC=CC=C3C4=NNN=N4)C([2H])=C2[2H]
Molecular Formula
C22H19D4ClN6O
Molecular Weight
426.94
Precautions
H302, H315, H319, H335
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
AT1 Receptor
Available Sizes
Curated Selection
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