MTC420
MTC420 (compound 42a) is a heterocyclic quinolone compound that targets the respiratory chain of Mycobacterium tuberculosis and exhibits antituberculosis activity (Rep Mtb: IC50=525 nM, Wayne Mtb: IC50=76 nM, MDR Mtb: IC50=140 nM) [1].
Product Specifications
CAS Number
2088930-66-7
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mtc420.html
Smiles
FC1=C2C(NC(C3=CC=C(N4CCC(C4)(F)F)C=C3)=C(C)C2=O)=CC(F)=C1
Molecular Formula
C20H16F4N2O
Molecular Weight
376.35
References & Citations
[1]Hong W D, et al. Rational design, synthesis, and biological evaluation of heterocyclic quinolones targeting the respiratory chain of Mycobacterium tuberculosis[J]. Journal of Medicinal Chemistry, 2017, 60 (9) : 3703-3726.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
HA723736 100 µL
KAT3B / p300 Recombinant Rabbit monoclonal Antibody
Sign In for Pricing
View Details ![SRP19 Recombinant Rabbit Monoclonal Antibody [JE59-23]](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea8172f/imageurl/ha720028.webp)
HA720028 100 µL
SRP19 Recombinant Rabbit Monoclonal Antibody [JE59-23]
Sign In for Pricing
View Details 
![AKR7A3 Mouse Monoclonal Antibody [Clone ID: AT2E11]](https://cdn.genprice.uk/products/937/68dd189e061270361e8fd61b/imageurl/am39004pu-n.webp)
AM39004PU-N 100 µL
AKR7A3 Mouse Monoclonal Antibody [Clone ID: AT2E11]
Sign In for Pricing
View Details 