Succimer

Succimer is a widely used chelating agent for the treatment of Pb poisoning.

Product Specifications

CAS Number

[304-55-2]

Product Name Alternative

Dimercaptosuccinic acid; DMSA

UNSPSC

12352211

Hazard Statement

H315, H319, H372, H413

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others; Cancer

Assay Protocol

https://www.medchemexpress.com/Succimer.html

Purity

99.36

Solubility

DMSO : ≥ 100 mg/mL|H2O : 4.72 mg/mL (ultrasonic; adjust pH to 8 with 1M NaOH)

Smiles

O=C(O)[C@@H](S)[C@@H](S)C(O)=O

Molecular Formula

C4H6O4S2

Molecular Weight

182.22

Precautions

H315, H319, H372, H413

References & Citations

[1]Gürer H, et al. Antioxidant effects of N-acetylcysteine and succimer in red blood cells from lead-exposed rats. Toxicology. 1998 Jul 17;128 (3) :181-9.|[2]Beaudin SA, et al. Succimer chelation normalizes reactivity to reward omission and errors in lead-exposed rats. Neurotoxicol Teratol. 2007 Mar-Apr;29 (2) :188-202.