GSK1016790A
GSK1016790A is a potent and selective transient receptor potential vanilloid 4 (TRPV4) channel agonist. GSK1016790A can elicit Ca2+ influx and elevate intracellular Ca2+ in HEK cells[1][2].
Product Specifications
CAS Number
[942206-85-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Calcium Channel; TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/GSK1016790A.html
Purity
99.93
Solubility
DMSO : ≥ 33 mg/mL|Methanol : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CC2=CC=CC=C2S1)N[C@H](C(N3CCN(C([C@@H](NS(=O)(C4=CC=C(Cl)C=C4Cl)=O)CO)=O)CC3)=O)CC(C)C
Molecular Formula
C28H32Cl2N4O6S2
Molecular Weight
655.61
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Calcium Channel; TRPV4
Available Sizes
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