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NU/ICRF 500

NU/ICRF 500 is a topo II catalytic inhibitor which increases CREST negative micronuclei in human lymphocytes[1].

Product Specifications

CAS Number

156074-08-7

UNSPSC

12352005

Target

Topoisomerase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/nu-icrf-500.html

Smiles

OC[C@H](NC1=C(C2=O)C(C(C3=C2C=CC=C3)=O)=C(O)C=C1)C(NN)=O

Molecular Formula

C17H15N3O5

Molecular Weight

341.32

References & Citations

[1]Cummings J, et al. Cytogenetic evaluation of the mechanism of cell death induced by the novel anthracenyl-amino acid topoisomerase II catalytic inhibitor NU/ICRF 500. Mutat Res. 1995 Aug;344 (1-2) :55-62.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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