NU/ICRF 500
NU/ICRF 500 is a topo II catalytic inhibitor which increases CREST negative micronuclei in human lymphocytes[1].
Product Specifications
CAS Number
156074-08-7
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nu-icrf-500.html
Smiles
OC[C@H](NC1=C(C2=O)C(C(C3=C2C=CC=C3)=O)=C(O)C=C1)C(NN)=O
Molecular Formula
C17H15N3O5
Molecular Weight
341.32
References & Citations
[1]Cummings J, et al. Cytogenetic evaluation of the mechanism of cell death induced by the novel anthracenyl-amino acid topoisomerase II catalytic inhibitor NU/ICRF 500. Mutat Res. 1995 Aug;344 (1-2) :55-62.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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