Fluphenazine-N-2-chloroethane (hydrochloride)

Fluphenazine-N-2-chloroethane (SKF-7171A) hydrochloride is a potent irreversible calmodulin antagonist[1][2].

Product Specifications

CAS Number

[3892-78-2]

Product Name Alternative

SKF-7171A (hydrochloride)

UNSPSC

12352005

Target

Calmodulin

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/fluphenazine-n-2-chloroethane-hydrochloride.html

Purity

95.5

Solubility

DMSO : 10 mg/mL (ultrasonic; warming)

Smiles

FC(C(C=C1N2CCCN3CCN(CCCl)CC3)=CC=C1SC4=C2C=CC=C4)(F)F.Cl.Cl

Molecular Formula

C22H27Cl3F3N3S

Molecular Weight

528.89

References & Citations

[1]D. R. Ishmael, et al. Trimetrexate, methotrexate, and pemetrexed results of comparative in vitro cytotoxicity and modulation by fluphenazine-N-2-chloroethane and leucovorin. 2005, Journal of Clinical Oncology. |[2]Moustafa A, et al. A novel role for carbon monoxide as a potent regulator of intracellular Ca2+ and nitric oxide in rat pancreatic acinar cells. Am J Physiol Cell Physiol. 2014 Dec 1;307 (11) :C1039-49.