Lenalidomide 5'-piperazine-4-methylpiperidine (hydrochloride)
Lenalidomide 5'-piperazine-4-methylpiperidine hydrochloride is a functionalized cerebellar ligand for PROTAC development, combining E3 ligand and terminal piperidine for subsequent chemical reactions. A protein degradant with a rigid connector is generated[1].
Product Specifications
CAS Number
[2520105-60-4]
UNSPSC
12352005
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lenalidomide-5-piperazine-4-methylpiperidine-hydrochloride.html
Purity
98.57
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1NC(C(CC1)N2C(C3=CC=C(N4CCN(CC5CCNCC5)CC4)C=C3C2)=O)=O.Cl.Cl
Molecular Formula
C23H33Cl2N5O3
Molecular Weight
498.45
References & Citations
[1]Yi Chen, et al. Mdm2 degrader. WO2023230059A1.2023-11-30.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
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