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11-​Keto-​beta-​boswellic acid

Product Specifications

UNSPSC Description

11-Keto-beta-boswellic acid (11-Keto-β-boswellic acid) is a pentacyclic triterpenic acid of the oleogum resin from the bark of the Boswellia serrate tree, popularly known as Indian Frankincense. 11-Keto-beta-boswellic acid has the anti-inflammatory activity is primarily due to inhibit 5-lipoxygenase (5-LOX) and subsequent leukotriene and nuclear factor-kappa B (NF-κB) activation and tumor necrosis factor alpha generation production[1].

Target Antigen

Leukotriene Receptor; Lipoxygenase; NF-κB

Type

Natural Products

Related Pathways

GPCR/G Protein;Metabolic Enzyme/Protease;NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/11-keto-beta-boswellic-acid.html

Purity

99.96

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

C[C@@]1([C@@]2(CC[C@]3(CC[C@H]([C@@H]([C@]3(C2=C4)[H])C)C)C)C)CC[C@@]5([H])[C@](C(O)=O)(C)[C@H](O)CC[C@]5(C)[C@@]1([H])C4=O

Molecular Weight

470.68

References & Citations

[1]Miscioscia E, et al. Measurement of 3-acetyl-11-keto-beta-boswellic acid and 11-keto-beta-boswellic acid in <i>Boswellia serrata</i> Supplements Administered to Dogs. BMC Vet Res. 2019 Aug 1;15(1):270.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N2056/11-Keto-beta-boswellic-acid-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N2056/11-Keto-beta-boswellic-acid-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

17019-92-0

Available Sizes

Curated Selection

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