Bortezomib analog 1
Bortezomib analog 1 is an analog of Bortezomib. Bortezomib analog 1 and can be used to synthesize PROTAC 20S proteasome subunit β5 degrader 1 (HY-169134).
Product Specifications
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bortezomib-analog-1.html
Smiles
CC1(C)[C@H]2[C@]3(C(OB([C@@H](NC([C@H](CC4=CC=CC=C4)NC(C5=CC=C(C(OC(C)(C)C)=O)C=C5)=O)=O)CC(C)C)O3)C[C@@H]1C2)C
Molecular Formula
C36H49BN2O6
Molecular Weight
616.60
References & Citations
[1]Wang S, et al. Discovery of novel 20S proteasome subunit β5 PROTAC degraders as potential therapeutics for pharyngeal carcinoma and Bortezomib-resistant multiple myeloma. Bioorg Chem. 2024 Sep 3;153:107801.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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