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Spizofurone

Spizofurone is an anti-ulcer compound with increased gastric mucosal blood flow activity and oral activity. Spizofurone has a similar mechanism of action to PGE2 (HY-101952), Spizofurone is capable of acting through local and systemic pathways and may promote ulcer healing by improving blood supply to the gastric mucosa. Spizofurone can be used to study the development strategy of gastric ulcer[1].

Product Specifications

CAS Number

[72492-12-7]

Product Name Alternative

AG-629

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/spizofurone.html

Smiles

O=C(C)C1=CC=C2OC3(CC3)C(C2=C1)=O

Molecular Formula

C12H10O3

Molecular Weight

202.21

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Inatomi N, et al. Spizofurone (AG-629) increases gastric mucosal blood flow in dogs: a possible mechanism of its anti-ulcer effect[J]. European journal of pharmacology, 1985, 110 (3) : 343-350.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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