Orotic acid (zinc)
Orotic acid (zinc), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid (zinc) is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid (zinc) can induce hepatic steatosis and hepatomegaly in rats[1][2][3].
Product Specifications
CAS Number
68399-76-8
Product Name Alternative
6-Carboxyuracil (zinc) ; Vitamin B13 (zinc)
UNSPSC
12352005
Target
Endogenous Metabolite; Nucleoside Antimetabolite/Analog
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/orotic-acid-zinc.html
Purity
99.84
Solubility
DMSO : 20 mg/mL (ultrasonic; adjust pH to 2 with 1 M HCl)
Smiles
O=C(C(NC1=O)=CC(N1)=O)O.[0.5Zn]
Molecular Formula
C5H4N2O4Zn0.5
Molecular Weight
188.79
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Human Endogenous Metabolite
Available Sizes
Frequently Asked Questions
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