CAIX Inhibitor S4
CAIX Inhibitor S4 is a potent and selective inhibitor of carbonic anhydrase IX/XII (CA IX/XII), with a Ki of 7 nM and 2 nM, respectively. CAIX Inhibitor S4 also inhibits CA II and CA I (Ki=546 and 5600 nM, respectively) . CAIX Inhibitor S4 can inhibit the number of lung metastasis in orthotopic MDA-MB-231 mouse model without affecting primary tumor growth[1].
Product Specifications
CAS Number
1330061-67-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/caix-inhibitor-s4.html
Purity
99.04
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC(C)=CC(C)=C1)NC2=CC=C(C=C2)OS(=O)(N)=O
Molecular Formula
C15H17N3O4S
Molecular Weight
335.38
Precautions
H302, H315, H319
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA IX
Available Sizes
Frequently Asked Questions
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