HDAC-MB

HDAC-MB a probe that is activated by HDAC6 and can detect and eliminate glioma cells through activation by HDAC6. HDAC-MB reveals antimetastatic and antiproliferative properties, inhibits glioma invasion and induces cellular apoptosis[1].

Product Specifications

UNSPSC

12171500

Target

Fluorescent Dye; Monoamine Oxidase

Type

Dye Reagents

Related Pathways

Neuronal Signaling; Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hdac-mb.html

Solubility

10 mM in DMSO

Smiles

CC(NCCCCCC(OC1=CC=C(C=C1)COC(N2C3=CC=C(C=C3SC4=CC(N(C)C)=CC=C42)N(C)C)=O)=O)=O

Molecular Formula

C32H38N4O5S

Molecular Weight

590.73

References & Citations

[1]Wei W, et al., HDAC6-Activatable Multifunctional Near-Infrared Probe for Glioma Cell Detection and Elimination. Anal Chem. 2024 Feb 13;96 (6) :2406-2414.