HDAC-MB
HDAC-MB a probe that is activated by HDAC6 and can detect and eliminate glioma cells through activation by HDAC6. HDAC-MB reveals antimetastatic and antiproliferative properties, inhibits glioma invasion and induces cellular apoptosis[1].
Product Specifications
UNSPSC
12171500
Target
Fluorescent Dye; Monoamine Oxidase
Type
Dye Reagents
Related Pathways
Neuronal Signaling; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac-mb.html
Solubility
10 mM in DMSO
Smiles
CC(NCCCCCC(OC1=CC=C(C=C1)COC(N2C3=CC=C(C=C3SC4=CC(N(C)C)=CC=C42)N(C)C)=O)=O)=O
Molecular Formula
C32H38N4O5S
Molecular Weight
590.73
References & Citations
[1]Wei W, et al., HDAC6-Activatable Multifunctional Near-Infrared Probe for Glioma Cell Detection and Elimination. Anal Chem. 2024 Feb 13;96 (6) :2406-2414.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
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