BMS-593214
Product Specifications
Product Name Alternative
GNF-Pf-1127
UNSPSC Description
BMS-593214 is an active site-directed factor (F) VIIa inhibitor. BMS-593214 shows antithrombotic and antihaemostatic properties. BMS-593214 is a direct competitive inhibitor of human FVIIa and a non-competitive inhibitor of Viia-activated substrate FX. BMS-593214 prevents electroinduced carotid artery thrombosis (AT) and wire induced vena cava thrombosis (VT)[1].
Target Antigen
Factor VIIa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bms-593214.html
Purity
99.90
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)C1=CC=C(C=C1)C2=CC(O)=C(C=C2[C@@H]3NC4=C([C@@]5([C@]3(CC6=C5C=CC=C6)[H])[H])C=C(C=C4)C(N)=N)OC
Molecular Weight
505.56
References & Citations
[1]Wong PC, et al. BMS-593214, an active site-directed factor VIIa inhibitor: enzyme kinetics, antithrombotic and antihaemostatic studies. Thromb Haemost. 2010 Aug;104(2):261-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114511/BMS-593214-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114511/BMS-593214-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1004551-40-9
Available Sizes
Curated Selection
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