BDW568
BDW568 is a STING agonist that can selectively activate the human STINGA230 allele. BDW568 can be used to activate STINGA230-engineered macrophages in macrophage-based immunotherapy[1].
Product Specifications
CAS Number
[335401-44-0]
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bdw568.html
Purity
99.4
Solubility
10 mM in DMSO
Smiles
COC(CSC1=NN=C2N1C=NC3=C2C(C)=C(C)S3)=O
Molecular Formula
C12H12N4O2S2
Molecular Weight
308.38
References & Citations
[1]Tang Z, et al. Structural Evaluations of a Selective Human STINGA230 Agonist and Its Use in Macrophage Immunotherapies[J]. ACS Medicinal Chemistry Letters, 2024.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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