Bursin
Bursin is a peptide that can be isolated from the bursa of Fabricius of chicken. Bursin induces the phenotypic differentiation of mammalian and avian B precursor cells. Bursin also increases cyclic guanosine monophosphate in cells of the human B-cell line Daudi, its derivatives are able to protect against infection by amplifying the immune response induced by H9N2[1].
Product Specifications
CAS Number
60267-34-7
UNSPSC
12352209
Target
Influenza Virus
Type
Peptides
Related Pathways
Anti-infection
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/bursin.html
Purity
99.35
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CNC([C@@H](NC([C@@H](N)CCCCN)=O)CC1=CNC=N1)=O)N
Molecular Formula
C14H25N7O3
Molecular Weight
339.39
References & Citations
[1]Audhya T, et al. Tripeptide structure of bursin, a selective B-cell-differentiating hormone of the bursa of fabricius. Science. 1986 Feb 28;231 (4741) :997-9.|[2]Wang C, et al. Bursin-like peptide (BLP) enhances H9N2 influenza vaccine induced humoral and cell mediated immune responses. Cell Immunol. 2014 Nov-Dec;292 (1-2) :57-64.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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